Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750828 | 0.81 | HTR1A (0.51) | DRD2SLC6A4OPRM1HSD11B1CTSS | |
| SCHEMBL4752455 | 0.81 | OPRM1 (0.47) | DRD2SLC6A4OPRL1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL4817572 | 0.79 | OPRM1 (0.45) | DRD2SLC6A4OPRL1OPRM1HSD11B1 | |
| SCHEMBL4750799 | 0.76 | POLB (0.42) | — | |
| SCHEMBL4752471 | 0.70 | OPRM1 (0.42) | DRD2OPRL1OPRM1HSD11B1 | |
| SCHEMBL4754022 | 0.68 | OPRM1 (0.49) | DRD2SLC6A4OPRM1HSD11B1 | |
| SCHEMBL4855972 | 0.67 | OPRL1 (0.65) | OPRL1OPRM1 | |
| SCHEMBL4750439 | 0.66 | SMN1; SMN2 (0.36) | DRD2SLC6A4 | |
| SCHEMBL4750861 | 0.66 | PLD2 (0.45) | DRD2OPRL1OPRM1HSD11B1 | |
| SCHEMBL4753001 | 0.65 | DRD2 (0.58) | DRD2SLC6A4OPRL1OPRM1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |