Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | FNTA | P49354 | 6/20 | 0.43 |
| ▸ | FNTB | P49356 | 6/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753126 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4753314 | 0.74 | NPSR1 (0.46) | OPRD1OPRK1FNTAFNTBPGGT1B | |
| SCHEMBL4751009 | 0.72 | APP (0.50) | ALDH1A1KDM4EMAPTNPC1HTT | |
| SCHEMBL4857441 | 0.71 | MEN1 (0.64) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4799893 | 0.70 | LMNA (0.50) | ALDH1A1MAPTNPC1POLB | |
| SCHEMBL13982579 | 0.70 | KDM4E (0.52) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL17485677 | 0.67 | KDM4E (0.74) | ALDH1A1GRIN2BKDM4EMAPTKMT2A | |
| SCHEMBL13150170 | 0.67 | KDM4E (0.60) | FNTAFNTBPGGT1BALDH1A1GRIN2B | |
| SCHEMBL20353636 | 0.66 | ALDH1A1 (0.74) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL8263854 | 0.65 | ALDH1A1 (0.55) | OPRD1OPRK1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |