Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753126 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17886713 | 0.76 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13982579 | 0.76 | KDM4E (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17886724 | 0.75 | MEN1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4751009 | 0.75 | APP (0.50) | ALDH1A1SMN1; SMN2MAPTSIGMAR1MAPK10 | |
| Hydrochloric Acid SCHEMBL31587154 | 0.73 | MEN1 (0.88) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13959029 | 0.73 | MEN1 (0.70) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4799893 | 0.73 | LMNA (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK10 | |
| SCHEMBL4751012 | 0.71 | OPRD1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5403356 | 0.70 | CYP2D6 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |