Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751628 | 0.92 | RAB9A (0.33) | KDM2B | |
| SCHEMBL4751362 | 0.91 | KDM2B (0.30) | KDM2B | |
| SCHEMBL4816419 | 0.83 | ESR1 (0.30) | ESR1 | |
| SCHEMBL4751598 | 0.82 | MET (0.30) | — | |
| SCHEMBL4751428 | 0.82 | KIF11 (0.34) | — | |
| SCHEMBL4776847 | 0.80 | ESRRG (0.33) | MEN1KMT2AKDM2BESR1 | |
| SCHEMBL4026066 | 0.79 | ESR1 (0.32) | MEN1KMT2AKDM2BESR1 | |
| SCHEMBL4025458 | 0.77 | NPC1 (0.36) | MEN1KMT2AKDM2B | |
| SCHEMBL4026418 | 0.77 | KDM1A (0.32) | KDM2BOPRM1OPRD1 | |
| SCHEMBL4809484 | 0.77 | ADRB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |