Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787216 | 0.84 | AKT1 (0.38) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL4752969 | 0.78 | PKM (0.46) | ALDH1A1CYP26A1CYP26B1MAPTPKM | |
| SCHEMBL4752450 | 0.75 | LMNA (0.36) | TSHRLMNAALDH1A1GAA | |
| SCHEMBL4868478 | 0.72 | LMNA (0.42) | LMNAALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL23667871 | 0.72 | SELL (0.37) | LMNAALDH1A1MAPTPKMGAA | |
| SCHEMBL4754019 | 0.70 | ALOX15 (0.37) | TSHRLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4750485 | 0.70 | HTR2A (0.51) | LMNAALDH1A1PKMNPSR1HTR2A | |
| SCHEMBL30079686 | 0.70 | ALOX15 (0.37) | TSHRLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL23667872 | 0.70 | HTR2A (0.38) | LMNAALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL29724666 | 0.70 | KMT2A (0.41) | LMNAALDH1A1MAPTPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |