Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | PLD2 | O14939 | 5/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4817572 | 0.90 | OPRM1 (0.45) | OPRM1OPRL1PLD2PLD1HSD11B1 | |
| SCHEMBL4750828 | 0.84 | HTR1A (0.51) | OPRM1PLD2PLD1HSD11B1CHRM1 | |
| SCHEMBL4753185 | 0.83 | DRD2 (0.51) | OPRM1OPRL1PLD2PLD1CHRM1 | |
| Hydrochloric Acid SCHEMBL4789324 | 0.81 | OPRL1 (0.48) | OPRM1OPRL1PLD2PLD1CHRM1 | |
| SCHEMBL4752455 | 0.79 | OPRM1 (0.47) | OPRM1OPRL1CHRM1DRD2HTR1A | |
| SCHEMBL4750861 | 0.79 | PLD2 (0.45) | OPRM1OPRL1PLD2PLD1HSD11B1 | |
| Hydrochloric Acid SCHEMBL4787868 | 0.74 | DRD2 (0.50) | OPRM1OPRL1PLD2PLD1CHRM1 | |
| Hydrochloric Acid SCHEMBL4788380 | 0.72 | OPRM1 (0.58) | OPRM1OPRL1CHRM1DRD2KCNH2 | |
| SCHEMBL4754022 | 0.71 | OPRM1 (0.49) | OPRM1PLD2PLD1HSD11B1CHRM1 | |
| Hydrochloric Acid SCHEMBL4787601 | 0.71 | OPRL1 (0.59) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | claimed |
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |