Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908879 | 0.88 | HTR7 (0.50) | HTR1AHTR2AHTR7ABCB1DRD2 | |
| SCHEMBL4750809 | 0.85 | DRD2 (0.44) | HTR1AHTR2AHTR7ABCB1DRD2 | |
| SCHEMBL4752410 | 0.82 | HTR2A (0.49) | HTR1AHTR2ADRD2 | |
| SCHEMBL4788339 | 0.78 | KCNH2 (0.50) | KCNH2HTR2AABCB1 | |
| Hydrochloric Acid SCHEMBL4789017 | 0.76 | KCNH2 (0.49) | KCNH2HTR2AABCB1 | |
| SCHEMBL4750506 | 0.75 | AKT1 (0.36) | HTR2A | |
| SCHEMBL4789257 | 0.74 | SMN1; SMN2 (0.49) | HTR1AKCNH2HTR2AABCB1 | |
| Hydrochloric Acid SCHEMBL4787404 | 0.73 | KCNH2 (0.51) | HTR1AKCNH2HTR7ABCB1DRD2 | |
| SCHEMBL4789463 | 0.73 | PPARG (0.44) | HTR1AHTR2AHTR7DRD2 | |
| SCHEMBL4786621 | 0.72 | SMN1; SMN2 (0.38) | HTR1AKCNH2HTR2AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |