Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4895520 | 0.86 | PPARG (0.43) | PPARGPPARAHTR7CXCR1HTR1A | |
| Hydrochloric Acid SCHEMBL4789652 | 0.84 | HTR7 (0.42) | PPARGPPARAHTR7CXCR1HTR1A | |
| SCHEMBL4908879 | 0.83 | HTR7 (0.50) | HTR7HTR1AHTR2AHTR2CDRD2 | |
| SCHEMBL4750809 | 0.73 | DRD2 (0.44) | HTR7PTGS2HTR1AALDH1A1SMN1; SMN2 | |
| SCHEMBL4752472 | 0.73 | HTR1A (0.53) | HTR7HTR1AHTR2ADRD2 | |
| SCHEMBL4752410 | 0.72 | HTR2A (0.49) | HTR1AHTR2ADRD2 | |
| SCHEMBL4750506 | 0.70 | AKT1 (0.36) | ALDH1A1HTR2A | |
| SCHEMBL6618898 | 0.70 | HTR7 (0.58) | PPARGPPARAHTR7HTR2CDRD2 | |
| SCHEMBL11269207 | 0.69 | HTR7 (0.60) | PPARGPPARAHTR7HTR2C | |
| SCHEMBL11278195 | 0.68 | HTR7 (0.55) | PPARGPPARAHTR7HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |