Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752472 | 0.85 | HTR1A (0.53) | DRD2HTR1AHTR2ACA1CA2 | |
| SCHEMBL4908879 | 0.85 | HTR7 (0.50) | DRD2HTR1AHTR2AABCB1HTR2C | |
| SCHEMBL4752410 | 0.81 | HTR2A (0.49) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL4754018 | 0.79 | LMNA (0.41) | DRD2ALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL4752984 | 0.78 | ALDH1A1 (0.36) | DRD2ALDH1A1LMNAKDM4EHSD17B10 | |
| SCHEMBL4750506 | 0.77 | AKT1 (0.36) | ALDH1A1LMNAKDM4EHTR2A | |
| SCHEMBL4750865 | 0.75 | HTR1A (0.48) | DRD2ALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL4789463 | 0.73 | PPARG (0.44) | DRD2ALDH1A1SMN1; SMN2HTR1AHTR2A | |
| SCHEMBL4788339 | 0.73 | KCNH2 (0.50) | HTR2ASIGMAR1ABCB1 | |
| Hydrochloric Acid SCHEMBL4789354 | 0.70 | HTR1A (0.39) | DRD2ALDH1A1LMNAKDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |