Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752472 | 0.88 | HTR1A (0.53) | HTR7HTR2AHTR1AABCB1DRD2 | |
| SCHEMBL4750809 | 0.85 | DRD2 (0.44) | HTR7HTR2AHTR1AHTR2CABCB1 | |
| SCHEMBL4789463 | 0.83 | PPARG (0.44) | HTR7HTR2AHTR1AHTR2CHTR6 | |
| SCHEMBL4754290 | 0.83 | HTR1A (0.50) | HTR7HTR2AHTR1AABCB1DRD2 | |
| SCHEMBL4751067 | 0.80 | HTR7 (0.47) | HTR7HTR2AHTR1AABCB1DRD2 | |
| SCHEMBL4752410 | 0.80 | HTR2A (0.49) | HTR2AHTR1ADRD2 | |
| SCHEMBL4788339 | 0.76 | KCNH2 (0.50) | HTR2AABCB1 | |
| Hydrochloric Acid SCHEMBL4789017 | 0.74 | KCNH2 (0.49) | HTR2AABCB1 | |
| SCHEMBL4750506 | 0.73 | AKT1 (0.36) | HTR2A | |
| SCHEMBL4754299 | 0.73 | ADRA1A (0.41) | HTR7HTR2AHTR1AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |