Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753094 | 0.85 | GNRHR (0.41) | TLR7KIF11BRD4GNRHRCYP3A4 | |
| SCHEMBL4096829 | 0.81 | KIF11 (0.44) | TLR7KIF11BRD4MALT1GNRHR | |
| SCHEMBL5250052 | 0.80 | KIF11 (0.40) | TLR7KIF11BRD4GNRHRNPSR1 | |
| SCHEMBL5248653 | 0.80 | KIF11 (0.42) | TLR7KIF11BRD4GNRHRCYP3A4 | |
| SCHEMBL4752600 | 0.79 | KIF11 (0.42) | TLR7KIF11CYP3A4SCN9ASCN10A | |
| SCHEMBL4753081 | 0.78 | KIF11 (0.45) | TLR7KIF11GNRHRNPSR1L3MBTL1 | |
| SCHEMBL5325935 | 0.78 | KIF11 (0.39) | TLR7KIF11BRD4GNRHRL3MBTL1 | |
| SCHEMBL4750950 | 0.75 | TLR7 (0.48) | TLR7KIF11BRD4GNRHRTDP1 | |
| SCHEMBL4752671 | 0.75 | PDE4A (0.42) | TLR7NPSR1L3MBTL1TDP1 | |
| SCHEMBL4098315 | 0.74 | LMNA (0.48) | TLR7NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |