Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753173 | 0.94 | MAPT (0.41) | CHRNB2CHRNA4MAPTPOLBALDH1A1 | |
| SCHEMBL4753368 | 0.85 | ALDH1A1 (0.45) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4751070 | 0.85 | ALDH1A1 (0.41) | MAPTALDH1A1LMNASMN1; SMN2CYP19A1 | |
| SCHEMBL4751068 | 0.85 | ALDH1A1 (0.41) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4750825 | 0.84 | ALDH1A1 (0.40) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4751039 | 0.84 | ALDH1A1 (0.45) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4750889 | 0.80 | POLB (0.42) | MAPTPOLBALDH1A1LMNAKDM4E | |
| SCHEMBL8549896 | 0.80 | CHRNB2 (0.45) | CHRNB2CHRNA4ALDH1A1KDM4EGAA | |
| SCHEMBL6734151 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL4044524 | 0.75 | LMNA (0.42) | MAPTPOLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |