SCHEMBL4755307

SCHEMBL4755307

CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 2/20 0.70
ALDH1A1 P00352 5/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
LIPG Q9Y5X9 1/20 0.47
TRPC5 Q9UL62 1/20 0.46
TSHR P16473 1/20 0.46
PRMT1 Q99873 1/20 0.46
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23918548 0.87 KMT2A (0.56) CASP3ALDH1A1MEN1KMT2ACHRM5
SCHEMBL23910448 0.87 MEN1 (0.58) CASP3ALDH1A1MEN1KMT2ALIPG
SCHEMBL1839329 0.86 CASP3 (0.69) CASP3ALDH1A1MEN1KMT2ATRPC5
SCHEMBL23918746 0.86 ALDH1A1 (0.55) CASP3ALDH1A1MEN1KMT2ATSHR
SCHEMBL2351123 0.84 CASP3 (0.57) CASP3ALDH1A1MEN1KMT2ATSHR
SCHEMBL23918738 0.83 CASP3 (0.51) CASP3ALDH1A1MEN1KMT2ALIPG
SCHEMBL9206443 0.83 CASP3 (0.50) CASP3ALDH1A1MEN1KMT2ALIPG
SCHEMBL27760325 0.83 CASP3 (1.00) CASP3ALDH1A1MEN1KMT2ATRPC5
SCHEMBL23918756 0.82 ALDH1A1 (0.51) CASP3ALDH1A1MEN1KMT2ALMNA
SCHEMBL24379688 0.82 ALDH1A1 (0.53) CASP3ALDH1A1MEN1KMT2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118649185-B Pharmaceutical composition for inhibiting enterococcus faecalis and application thereof 昆明市延安医院(昆明市干部疗养院) 2025-03-04 CN claimed
CN-118649185-A Pharmaceutical composition for inhibiting enterococcus faecalis and application thereof 昆明市延安医院(昆明市干部疗养院) 2024-09-17 CN claimed
US-11504406-B2 Probiotic and probiotic combination for inhibition of vancomycin-resistant enterococci and use thereof DELTA ELECTRONICS, INC. (TW) 2022-11-22 US claimed
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES CureVac SE (DE) 2026-04-02 US disclosed
US-12576040-B2 Ionizable lipids and methods of manufacture and use thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-03-17 US disclosed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP disclosed
EP-4661910-A2 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2025-12-17 EP disclosed
EP-4662196-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2025-12-17 EP disclosed
US-20250367131-A1 IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF George Mason Research Foundation, Inc. 2025-12-04 US disclosed
US-20250360199-A1 IMMUNOGENS AND METHODS FOR INDUCING AN IMMUNE RESPONSE US HEALTH (US) 2025-11-27 US disclosed
US-20250352636-A1 NUCLEIC ACID COMPRISING OR CODING FOR A HISTONE STEM-LOOP AND A POLY(A) SEQUENCE OR A POLYADENYLATION SIGNAL FOR INCREASING THE EXPRESSION OF AN ENCODED PATHOGENIC ANTIGEN CureVac SE (DE) 2025-11-20 US disclosed
US-10161929-B2 Theranostics platform and methods of use Sanford Burnham Prebys Medical Discovery (US) 2018-12-25 US disclosed
US-9034798-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2015-05-19 US disclosed
US-8569481-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PHARMACEUTICALS, INC. (US) 2013-10-29 US disclosed
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions KOESTER HUBERT 2011-05-19 US disclosed
US-20100298168-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions HK PHARMACEUTICALS, INC. 2010-11-25 US disclosed
US-20100248264-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions HK PHARMACEUTICALS, INC. 2010-09-30 US disclosed
WO-2008156654-A2 CYTOSKELETON MODULATORS FOR TREATING METABOLIC DISORDERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-12-24 WO disclosed
US-20060062822-A1 Medical devices to treat or inhibit restenosis MEDTRONIC VASCULAR, INC. (US) 2006-03-23 US disclosed
US-20050004225-A1 Oxidoreductase inhibitors and methods of screening and using thereof CITY OF HOPE 2005-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576040-B2 Ionizable lipids and methods of manufacture and use thereof NPC1L1, NSUN3, CETP CASP3 2016/4885ALDH1A1 1813/4885MEN1 1850/4885
US-20250352636-A1 NUCLEIC ACID COMPRISING OR CODING FOR A HISTONE STEM-LOOP AND A POLY(A) SEQUENCE OR A POLYADENYLATION SIGNAL FOR INCREASING THE EXPRESSION OF AN ENCODED PATHOGENIC ANTIGEN HNRNPH3, PARG, CPSF6 CASP3 4027/4885ALDH1A1 4188/4885MEN1 1143/4885
US-20250367131-A1 IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF NPC1L1, PLA2G4A, PLA2G2A CASP3 3927/4885ALDH1A1 2988/4885MEN1 1295/4885
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PTMS, QPCTL, SRMS CASP3 4716/4885ALDH1A1 4360/4885MEN1 3426/4885
US-20060062822-A1 Medical devices to treat or inhibit restenosis ALDOA, AKR1B1, AKR1C2 CASP3 3779/4885ALDH1A1 11/4885MEN1 2391/4885
US-20100298168-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CHLSN, PTMS, SRMS CASP3 3901/4885ALDH1A1 4064/4885MEN1 2224/4885
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES RNMT, NSUN3, SARNP CASP3 3627/4885ALDH1A1 2988/4885MEN1 4351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.