Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.31 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.31 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939279 | 0.86 | PTGDR2 (0.37) | ALDH1A1POLBMAPTHPGDMAPK1 | |
| SCHEMBL4935850 | 0.78 | NPC1 (0.37) | ALDH1A1POLBMAPTMAPK1TSHR | |
| SCHEMBL4757355 | 0.76 | PYGM (0.39) | ALDH1A1GAACRHBPCRHR2HTT | |
| SCHEMBL3392135 | 0.71 | POLB (0.45) | ALDH1A1POLBMAPTMAPK1TSHR | |
| SCHEMBL5444348 | 0.71 | LMNA (0.38) | ALDH1A1MAPTGAAGPBAR1KMT2A | |
| SCHEMBL10951083 | 0.67 | MAOB (0.44) | MAPTMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL4758577 | 0.67 | TSHR (0.36) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL4758583 | 0.65 | PYGL (0.38) | ALDH1A1MAPTHPGDTSHRGAA | |
| SCHEMBL4758043 | 0.65 | CRHBP (0.40) | ALDH1A1POLBMAPTHPGDMAPK1 | |
| SCHEMBL9101372 | 0.63 | TSHR (0.37) | ALDH1A1MAPTHPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | claimed |
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-1858325-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | Roskamp Research LLC (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006074419-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | ROSKAMP RESEARCH LLC (US) | 2006-07-13 | — | — | WO | disclosed |