Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAPDH | P04406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426063 | 0.84 | LMNA (0.66) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL9853158 | 0.84 | LMNA (0.66) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL8194585 | 0.82 | LMNA (0.64) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL8194587 | 0.82 | LMNA (0.64) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL28887946 | 0.81 | MAPT (0.74) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL7749569 | 0.80 | SMN1; SMN2 (0.69) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL1862223 | 0.79 | HCAR2 (0.69) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL369705 | 0.79 | HCAR2 (0.69) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL5598744 | 0.79 | HCAR2 (0.74) | LMNASMN1; SMN2HPGDHCAR2NPC1 | |
| SCHEMBL5598741 | 0.79 | HCAR2 (0.74) | LMNASMN1; SMN2HPGDHCAR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | claimed |
| EP-0146277-B1 | CELLULOSIC PRODUCTS | A.E. STALEY MANUFACTURING COMPANY (US) | 1990-11-14 | — | — | EP | claimed |
| EP-4263511-A1 | NOVEL BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION | Amphista Therapeutics Ltd (GB) | 2023-10-25 | — | — | EP | disclosed |
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |
| WO-2022129925-A1 | NOVEL BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| US-9079931-B2 | Ruthenium complex and method for preparing optically active alcohol compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-07-14 | — | — | US | disclosed |
| EP-2563799-B1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | TAKASAGO PERFUMERY CO LTD (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-20130041151-A1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-14 | — | — | US | disclosed |
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | disclosed |
| US-20040082794-A1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1411045-A1 | Process for production of optically active amino alcohols | Yokozawa, Tohru (JP) | 2004-04-21 | — | — | EP | disclosed |
| EP-0146277-B1 | CELLULOSIC PRODUCTS | A.E. STALEY MANUFACTURING COMPANY (US) | 1990-11-14 | — | — | EP | disclosed |
| EP-0146277-A2 | Cellulosic products | A.E. STALEY MANUFACTURING COMPANY (US) | 1985-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041151-A1 | RUTHENIUM COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE ALCOHOL COMPOUND | ADH5, ADH1C, ADH1A | LMNA 4045/4885SMN1; SMN2 4807/4885HPGD 757/4885 |
| US-20040082794-A1 | Process for production of optically active amino alcohols | ADH5, ADH1C, ADH1A | LMNA 3886/4885SMN1; SMN2 4253/4885HPGD 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.