Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755836 | 1.00 | PHGDH (0.33) | PHGDHAVPR1ATRPV3PIK3CAPDE4B | |
| SCHEMBL4755659 | 0.88 | MEN1 (0.39) | SMN1; SMN2 | |
| SCHEMBL4755656 | 0.88 | MEN1 (0.39) | SMN1; SMN2 | |
| SCHEMBL4755169 | 0.87 | AVPR1A (0.39) | AVPR1ASMN1; SMN2KCNH2 | |
| SCHEMBL4755166 | 0.87 | AVPR1A (0.39) | AVPR1ASMN1; SMN2KCNH2 | |
| SCHEMBL4755594 | 0.87 | DRD1 (0.37) | SMN1; SMN2 | |
| SCHEMBL4755592 | 0.87 | DRD1 (0.37) | SMN1; SMN2 | |
| SCHEMBL4753245 | 0.85 | DRD2 (0.41) | AVPR1ANR1H2NR1H3SMN1; SMN2KCNH2 | |
| SCHEMBL4753244 | 0.85 | DRD2 (0.41) | AVPR1ANR1H2NR1H3SMN1; SMN2KCNH2 | |
| SCHEMBL13985302 | 0.85 | TSHR (0.31) | AVPR1ANR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |