Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3909671 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL8839908 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL17447343 | 0.59 | — | — | |
| SCHEMBL17208384 | 0.56 | — | — | |
| SCHEMBL25452830 | 0.55 | TSHR (0.39) | — | |
| SCHEMBL24868147 | 0.55 | — | — | |
| Propionic Acid SCHEMBL11050406 | 0.53 | FFAR3 (0.50) | — | |
| Bicarbonate SCHEMBL15841470 | 0.53 | CA4 (0.44) | — | |
| Bicarbonate SCHEMBL7168833 | 0.53 | — | — | |
| Propionic Acid SCHEMBL27633134 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |