Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756548 | 0.81 | GAA (0.46) | HPDALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL4756572 | 0.72 | TTR (0.43) | MAPK1HPDKDM4EPDE4D | |
| SCHEMBL4753206 | 0.71 | MAPK1 (0.45) | MAPK1HPDKMT2AMEN1 | |
| SCHEMBL4756570 | 0.69 | ALDH1A1 (0.50) | MAPK1ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL8755640 | 0.69 | PLAU (0.55) | ALDH1A1KDM4EHPGDNEU3KMT2A | |
| SCHEMBL8901022 | 0.67 | ADORA3 (0.44) | PTGFRALDH1A1KDM4EHPGDNEU3 | |
| SCHEMBL9954001 | 0.67 | PDE4D (0.56) | HPDALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8892083 | 0.67 | ALDH1A1 (0.43) | PTGFRALDH1A1KDM4EHPGDNEU3 | |
| SCHEMBL28232030 | 0.65 | ALDH1A1 (0.51) | MAPK1ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL9954671 | 0.65 | HCAR1 (0.52) | HPDPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |