Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756572 | 0.80 | TTR (0.43) | MAPK1HPDNPSR1L3MBTL1 | |
| SCHEMBL4755109 | 0.77 | SMN1; SMN2 (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL4756570 | 0.76 | ALDH1A1 (0.50) | MAPK1MEN1KMT2AMAPT | |
| SCHEMBL4756548 | 0.74 | GAA (0.46) | MEN1KMT2AHPDMAPT | |
| SCHEMBL9954526 | 0.72 | POLB (0.54) | MAPTATM | |
| SCHEMBL4756539 | 0.71 | PTGFR (0.41) | MAPK1MEN1KMT2AHPD | |
| SCHEMBL11270745 | 0.68 | ALPG (0.67) | MEN1KMT2A | |
| SCHEMBL9953980 | 0.66 | ATM (0.51) | MEN1KMT2AL3MBTL1MAPTATM | |
| SCHEMBL9953324 | 0.66 | HCAR1 (0.50) | MAPK1 | |
| SCHEMBL18950565 | 0.66 | HSD17B10 (0.70) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |