Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672982 | 0.73 | POLB (0.34) | POLB | |
| SCHEMBL11362806 | 0.69 | MAPK1 (0.35) | PLA2G7LMNAHSD17B10 | |
| SCHEMBL2239480 | 0.67 | POLB (0.38) | POLB | |
| SCHEMBL4789828 | 0.67 | LMNA (0.47) | POLBLMNA | |
| SCHEMBL14009878 | 0.67 | PLA2G7 (0.42) | PLA2G7POLBLMNAHSD17B10 | |
| SCHEMBL2240848 | 0.65 | POLB (0.36) | POLB | |
| SCHEMBL3684127 | 0.65 | L3MBTL1 (0.34) | — | |
| SCHEMBL417571 | 0.65 | PLA2G7 (0.39) | PLA2G7POLBLMNAHSD17B10 | |
| SCHEMBL2960814 | 0.64 | ALDH1A1 (0.33) | POLBLMNA | |
| SCHEMBL2964264 | 0.63 | GLA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |