SCHEMBL417571

SCHEMBL417571

CN1C(=O)N(C)C(C)(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.39
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.36
AR P10275 1/20 0.35
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765313 0.76 LMNA (0.36) LMNAPOLB
SCHEMBL26934774 0.76 LMNA (0.31) PLA2G7LMNA
SCHEMBL1363456 0.74 LMNA (0.34) LMNA
SCHEMBL16683834 0.74 AR (0.35) PLA2G7LMNAAR
SCHEMBL7021223 0.74 PLA2G7 (0.37) PLA2G7LMNAHSD17B10AR
SCHEMBL25488449 0.74 PLA2G7 (0.37) PLA2G7LMNAHSD17B10AR
SCHEMBL19014728 0.74 PLA2G7 (0.37) PLA2G7LMNAHSD17B10AR
SCHEMBL7058181 0.74 LMNA (0.34) LMNA
SCHEMBL16702762 0.74 PLA2G7 (0.37) PLA2G7LMNAHSD17B10AR
SCHEMBL6563168 0.74 PLA2G7 (0.37) PLA2G7LMNAHSD17B10AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3931288-B1 LUBRICATING COMPOSITION FOR PREVENTING OR REDUCING PRE-IGNITION IN AN ENGINE TOTALENERGIES ONETECH (FR) 2023-12-20 EP claimed
CN-115364692-B Air filtration composite membrane prepared based on cellulose nanofiber reinforced hydrogel conversion and preparation method thereof 中国科学院上海高等研究院 2023-08-25 CN claimed
CN-115364692-A Air filtration composite membrane prepared based on cellulose nanofiber reinforced hydrogel conversion and preparation method thereof 中国科学院上海高等研究院 2022-11-22 CN claimed
WO-2022119431-A1 PHARMACEUTICAL COMPOSITION HAVING AN ANALGAESIC AND AN ANTIHISTAMINE FOR TREATING RESPIRATORY DISEASES LABORATORIOS SILANES S.A. DE C.V. (MX) 2022-06-09 WO claimed
CN-113474441-A Lubricating composition for preventing or reducing pre-ignition in an engine 道达尔销售服务公司 2021-10-01 CN claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-10292967-B2 Compositions comprising corneoscleral tissue cross-linking agents THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-05-21 US claimed
EP-3378313-A1 COMPOSITIONS CONTAINING POLYMERIC, IONIC COMPOUNDS COMPRISING IMIDAZOLIUM GROUPS BASF SE (DE) 2018-09-26 EP claimed
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups BASF SE (DE) 2018-07-10 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-6103739-A BONE RESORPTION; ANTIINFLAMMATORY AGENTS, SKIN DISORDERS; ANTITUMOR-CARCINOGENIC AND METASTASES AGENTS; ANGIOGENESIS INHIBITORS; ANTIARRITHIC AGENTS; RHEUMATOID DISEASES; OSTEOARTHRITIS, PERIODONTITIS, GINGIVITIS AND CORNEAL ULCERS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-08-15 US claimed
EP-0944597-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-29 EP claimed
EP-0865339-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-09-23 EP claimed
WO-1998023588-A9 METALLOPROTEINASE INHIBITORS 1998-09-17 WO claimed
WO-1998023588-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-06-04 WO claimed
WO-1997003783-A9 METALLOPROTEINASE INHIBITORS 1997-04-03 WO claimed
WO-1997003783-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-02-06 WO claimed
US-5480633-A LOW LEVELS OF NONIONIC SURFACTANT AND ORGANIC ACID IN WATER; SOAP AND SURFACTANT RESIDUE REMOVAL; SENSITIVITY; LIQUID OR GEL COLGATE-PALMOLIVE COMPANY (US) 1996-01-02 US claimed
EP-0359803-A1 PROCESS FOR STABILIZING PHOTOGRAPHIC ELEMENTS. EASTMAN KODAK CO (US) 1990-03-28 EP claimed
WO-1989008870-A1 PROCESS FOR STABILIZING PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (US) 1989-09-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10292967-B2 Compositions comprising corneoscleral tissue cross-linking agents SMCHD1, ALDH1A2, CRYAB PLA2G7 1288/4885LMNA 2353/4885HSD17B10 644/4885
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN PLA2G7 2819/4885LMNA 336/4885HSD17B10 2953/4885
US-10016354-B2 Compositions containing polymeric, ionic compounds comprising imidazolium groups PUF60, POLR1C, PICALM PLA2G7 4224/4885LMNA 2122/4885HSD17B10 3533/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM PLA2G7 2655/4885LMNA 455/4885HSD17B10 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.