Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672982 | 0.74 | POLB (0.34) | POLB | |
| SCHEMBL14404412 | 0.67 | LMNA (0.56) | LMNAELANEPRTN3CTSG | |
| SCHEMBL3684127 | 0.67 | L3MBTL1 (0.34) | — | |
| SCHEMBL4756858 | 0.67 | PLA2G7 (0.35) | LMNAPOLB | |
| SCHEMBL2960814 | 0.65 | ALDH1A1 (0.33) | LMNAPOLB | |
| SCHEMBL2964264 | 0.64 | GLA (0.30) | — | |
| Trimethadione SCHEMBL28882 | 0.64 | LMNA (1.00) | LMNAELANEPRTN3CTSG | |
| SCHEMBL4599921 | 0.64 | POLB (0.31) | POLB | |
| SCHEMBL30779753 | 0.63 | GLA (0.41) | POLB | |
| SCHEMBL18084352 | 0.63 | POLB (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |