Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757771 | 0.80 | PDK4 (0.45) | TRPV1 | |
| SCHEMBL4755073 | 0.73 | FDFT1 (0.39) | ALDH1A1MAPTHPGDDRD2 | |
| SCHEMBL4758256 | 0.72 | HTR2C (0.46) | SIGMAR1MAPT | |
| SCHEMBL4755099 | 0.69 | TRPV1 (0.36) | PPARGPPARATRPV1SIGMAR1KDM4E | |
| SCHEMBL4192586 | 0.68 | HDAC4 (0.56) | SIGMAR1KDM4EALDH1A1MAPTTDP1 | |
| Lithium Ion SCHEMBL4755102 | 0.68 | TRPV1 (0.35) | PPARGPPARATRPV1SIGMAR1KDM4E | |
| SCHEMBL2662880 | 0.68 | CA12 (0.62) | TRPV1L3MBTL1 | |
| SCHEMBL7589274 | 0.68 | CA12 (0.62) | TRPV1KDM4E | |
| SCHEMBL15615318 | 0.67 | CA12 (0.56) | TRPV1L3MBTL1 | |
| SCHEMBL23448820 | 0.66 | QDPR (0.56) | KDM4EALDH1A1MAPTUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |