Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 3/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944380 | 0.82 | QDPR (0.51) | HTR2CSIGMAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4185793 | 0.81 | QDPR (0.50) | HTR2CSIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28688462 | 0.75 | SIGMAR1 (0.69) | HTR2CSIGMAR1HTR6MAPTHTR1B | |
| Hydrochloric Acid SCHEMBL28678896 | 0.73 | HTR2C (0.70) | HTR2CSIGMAR1HTR6FTOMAPT | |
| SCHEMBL2662880 | 0.73 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7589274 | 0.73 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4756934 | 0.72 | PPARG (0.44) | SIGMAR1MAPT | |
| SCHEMBL4757771 | 0.71 | PDK4 (0.45) | — | |
| SCHEMBL15787045 | 0.71 | IMPDH2 (0.58) | HTR2CHTR6MAPT | |
| SCHEMBL4869840 | 0.71 | TSHR (0.56) | SLC6A2SLC6A4SLC6A3MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |