Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654179 | 0.77 | CYP1A1 (0.46) | ALDH1A1KMT2AMAPT | |
| SCHEMBL10495730 | 0.75 | CA12 (0.47) | ALDH1A1MAOAMAOBCHRNB2CHRNB4 | |
| SCHEMBL15856977 | 0.75 | NPC1 (0.47) | ALDH1A1TSHRESR1MAPTHPGD | |
| SCHEMBL7835696 | 0.75 | CYP19A1 (0.41) | ALDH1A1MAOAMAOBTSHRESR1 | |
| SCHEMBL11617330 | 0.75 | MAOA (0.49) | ALDH1A1HTTMAOAMAOBKMT2A | |
| SCHEMBL1025762 | 0.75 | CA2 (0.47) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL6402484 | 0.74 | ALDH1A1 (0.61) | ALDH1A1HTTMAOAMAOBKMT2A | |
| SCHEMBL6278292 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4654471 | 0.73 | MAOA (0.37) | ALDH1A1HTTMAOAMAOBKMT2A | |
| SCHEMBL16591748 | 0.72 | MAOB (0.40) | ALDH1A1MAOAMAOBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306369-B1 | NOVEL SULFUR COMPOUNDS AND INTERMOLECULAR COMPOUNDS CONTAINING THE SAME AS THE COMPONENT COMPOUND | NIPPON SODA CO (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-6927309-B2 | Sulfur compounds and intermolecular compounds containing the same as the component compounds | NIPPON SODA CO., LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20040176643-A1 | Novel sulfur compounds and intermolecular compounds containing the same as the component compounds | NIPPON SODA CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1306369-A1 | NOVEL SULFUR COMPOUNDS AND INTERMOLECULAR COMPOUNDS CONTAINING THE SAME AS THE COMPONENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2003-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176643-A1 | Novel sulfur compounds and intermolecular compounds containing the same as the component compounds | CBS, TST, ABCB7 | ALDH1A1 1370/4885HTT 2246/4885MAOA 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.