SCHEMBL47581

SCHEMBL47581

CC(C)(C)c1ccc(C(C)(C)C)s1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
YEATS4 O95619 1/20 0.42
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
TSHR P16473 2/20 0.37
LMNA P02545 2/20 0.37
MAPK14 Q16539 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TYR P14679 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21841894 0.88 MAPK1 (0.39) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL21775973 0.86 MAPK1 (0.38) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL12264366 0.86 MAPK1 (0.47) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL14997805 0.86 DAO (0.45) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL12210930 0.86 MAPK1 (0.38) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL25451234 0.86 MAPK1 (0.38) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL12737778 0.84 MAPK1 (0.41) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL279712 0.82 MAPK1 (0.39) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL498360 0.82 MAPK1 (0.39) MAPK1KMT2AYEATS4NPC1RAB9A
SCHEMBL14379745 0.82 MAPK1 (0.39) MAPK1KMT2AYEATS4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428202-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2019-01-16 EP claimed
US-9611348-B2 Process of producing polyolefins using metallocene polymerization catalysts and copolymers therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-04-04 US claimed
EP-2984111-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2016-02-17 EP claimed
US-20140316085-A1 Process of Producing Polyolefins Using Metallocene Polymerization Catalysts and Copolymers Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US claimed
WO-2014169017-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-16 WO claimed
US-12024528-B2 Bridged tricyclic carbamoylpyridone compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-02 US disclosed
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders ARDELYX, INC. (US) 2024-06-25 US disclosed
WO-2024085690-A1 CURRENT COLLECTOR FOR ELECTRODE 주식회사 엘지화학 2024-04-25 WO disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240018279-A1 Cyclic Containing Polymer Compositions Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-18 US disclosed
US-11840521-B2 Modulators of Mas-related G-protein receptor X4 and related products and methods ESCIENT PHARMACEUTICALS, INC. (US) 2023-12-12 US disclosed
US-11840521-B2 Modulators of Mas-related G-protein receptor X4 and related products and methods ESCIENT PHARMACEUTICALS, INC. (US) 2023-12-12 US disclosed
US-7335753-B2 Bifunctional heterocyclic compounds and methods of making and using same RIB-X PHARMACEUTICALS, INC. (US) 2008-02-26 US disclosed
US-20080020127-A1 Methods and systems for coating a medical device ALLACCEM, INC. 2008-01-24 US disclosed
US-20080021212-A1 Methods and systems for preparing an antimicrobial composition ALLACCEM, INC. 2008-01-24 US disclosed
US-20070202342-A1 Applying to an oral surface (teeth or gums)one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning; dentistry; bonding agents, resin cements, sealants ALLACCEM, INC. 2007-08-30 US disclosed
US-20070149598-A1 M3 muscarinic acetylcholine receptor antagonists GLAXO GROUP LIMITED (GB) 2007-06-28 US disclosed
US-20070149598-A1 M3 muscarinic acetylcholine receptor antagonists GLAXO GROUP LIMITED (GB) 2007-06-28 US disclosed
US-20070072811-A1 Bifunctional heterocyclic compounds and methods of making and using the same RIB-X PHARMACEUTICALS, INC. 2007-03-29 US disclosed
US-5234790-A Peel-apart photosensitive element E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840521-B2 Modulators of Mas-related G-protein receptor X4 and related products and methods MRGPRX4, MRGPRX1, MRGPRX2 MAPK1 1068/4885KMT2A 4004/4885YEATS4 1243/4885
US-20070072811-A1 Bifunctional heterocyclic compounds and methods of making and using the same PCNA, DCX, HPGDS MAPK1 2437/4885KMT2A 4064/4885YEATS4 3858/4885
US-20080021212-A1 Methods and systems for preparing an antimicrobial composition DNMT1, TET2, POLR1C MAPK1 3686/4885KMT2A 1094/4885YEATS4 3989/4885
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 MAPK1 2729/4885KMT2A 1342/4885YEATS4 984/4885
US-20070149598-A1 M3 muscarinic acetylcholine receptor antagonists CHRM3, CHRM2, CHRM5 MAPK1 4123/4885KMT2A 2669/4885YEATS4 3905/4885
US-12024528-B2 Bridged tricyclic carbamoylpyridone compounds and uses thereof SDHA, SDHB, DPYD MAPK1 4148/4885KMT2A 3060/4885YEATS4 3814/4885
US-12016856-B2 Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders SLC10A1, SLC10A2, FABP3 MAPK1 2648/4885KMT2A 3647/4885YEATS4 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.