SCHEMBL4758768

SCHEMBL4758768

CCCCOCN(COCCCC)c1nc(N)nc(N)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
PKM P14618 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NOS1 P29475 1/20 0.38
MAPT P10636 1/20 0.36
CDK1 P06493 3/20 0.36
CCNB1 P14635 3/20 0.36
CCNA2 P20248 2/20 0.36
CDK2 P24941 2/20 0.36
CCNA1 P78396 2/20 0.36
PIN1 Q13526 1/20 0.36
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MCHR1 Q99705 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.32
HRH2 P25021 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11126960 0.96 MAPT (0.39) LMNAPKMSMN1; SMN2NOS1MAPT
SCHEMBL2009963 0.94 LMNA (0.35) LMNAPKMSMN1; SMN2NOS1MAPT
Formaldehyde SCHEMBL918417 0.89 LMNA (0.33) LMNAPKMSMN1; SMN2NOS1MAPT
SCHEMBL237936 0.87 TSHR (0.38) SMN1; SMN2MAPTHTTMEN1KMT2A
SCHEMBL11412991 0.84 ALDH1A1 (0.36) LMNAPKMSMN1; SMN2NOS1MAPT
SCHEMBL11760856 0.83 SLC29A1 (0.35) LMNAPKMSMN1; SMN2NOS1MAPT
SCHEMBL14081584 0.81 TSHR (0.41) LMNASMN1; SMN2MAPTHTTHSD17B10
SCHEMBL11857194 0.81 TSHR (0.34) SMN1; SMN2MAPTHTTMEN1KMT2A
SCHEMBL27729331 0.81 LMNA (0.35) LMNAPKMSMN1; SMN2NOS1CDK1
SCHEMBL15437935 0.81 MAPT (0.38) SMN1; SMN2NOS1MAPTHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1279686-B1 Polymers from triazine derivatives AMI AGROLINZ MELAMINE INT GMBH (AT) 2008-08-20 EP disclosed
US-6818726-B2 FOR INTERMEDIATES AND MOLDED MATERIALS WITH IMPROVED TOUGHNESS AND HIGH FLAME RESISTANCE AND STRENGTH AGROLINZ MELAMIN GMBH (AT) 2004-11-16 US disclosed
US-6818768-B2 20-70% BY WEIGHT TRIAZINE DERIVATIVES WITH HYDROXYALKYL AMINO GROUPS AND 30-80% OF TRIAZINE DERIVATIVES WITH BIS/HYDROXYLAKYL)IMINO GROUP AGROLINZ MELAMIN GMBH (AT) 2004-11-16 US disclosed
US-20030050474-A1 Mixtures of triazine derivatives free from polyalkylene oxide AGROLINZ MELAMIN GMBH (AT) 2003-03-13 US disclosed
US-20030045667-A1 Polymers made from triazine derivatives AGROLINZ MELAMIN GMBH (AT) 2003-03-06 US disclosed
EP-1279669-A2 Polyalkylene oxide-free mixture of triazine derivatives Agrolinz Melamin GmbH (AT) 2003-01-29 EP disclosed
EP-1279686-A2 Polymers from triazine derivatives Agrolinz Melamin GmbH (AT) 2003-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030050474-A1 Mixtures of triazine derivatives free from polyalkylene oxide TAAR5, TAAR1, ARNT LMNA 2464/4885PKM 1818/4885SMN1; SMN2 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.