Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18382968 | 0.82 | KDM4E (0.43) | L3MBTL1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL29291582 | 0.82 | GAA (0.40) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL3056019 | 0.80 | KDM4E (0.46) | MAPTL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL4350886 | 0.80 | KDM4E (0.45) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL1889853 | 0.80 | L3MBTL1 (0.43) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL4166587 | 0.80 | KDM4E (0.46) | L3MBTL1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2363096 | 0.80 | L3MBTL1 (0.43) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL3138514 | 0.80 | POLB (0.43) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL19556155 | 0.78 | L3MBTL1 (0.42) | MAPTL3MBTL1POLBTDP1KDM4E | |
| SCHEMBL2373838 | 0.78 | KDM4E (0.62) | MAPTL3MBTL1POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768795-A | Synthesis method of cyenopyrafen intermediate | 湖南速博生物技术有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-107216288-A | A kind of preparation method of Tolfenpyrad impurity | 湖南大学 | 2017-09-29 | — | — | CN | claimed |
| WO-2025049827-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES | OSMO LABS, PBC (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025022637-A1 | METHOD FOR PRODUCING CYCLIZED PRODUCT BY CYCLIZATION REACTION INVOLVING DEHYDRATION CONDENSATION OF CARBOXYLIC ACID ESTER DERIVATIVE, AND METHOD FOR PRODUCING 1,3,4-SUBSTITUTED-PYRAZOLE-5-CARBOXYLIC ACID ESTER | 株式会社日本ファインケム | 2025-01-30 | — | — | WO | disclosed |
| CN-112119076-B | Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors | 默沙东有限责任公司 | 2025-01-10 | — | — | CN | disclosed |
| EP-3788043-B1 | SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |
| CN-117986190-B | Method for synthesizing ethyl trimethylpyrazole | 德州新势立精细化工有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117986190-A | Method for synthesizing ethyl trimethylpyrazole | 德州新势立精细化工有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116768795-A | Synthesis method of cyenopyrafen intermediate | 湖南速博生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116768795-A | Synthesis method of cyenopyrafen intermediate | 湖南速博生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113354677-B | Acrylonitrile compound and preparation method and application thereof | 华中师范大学 | 2023-08-01 | — | — | CN | disclosed |
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170114021-A1 | HALOGEN-SUBSTITUTED COMPOUNDS | BAYER ANIMAL HEALTH GMBH (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20150099766-A1 | Novel halogen-substituted compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-09 | — | — | US | disclosed |
| US-8946234-B2 | Halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| WO-2012069601-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| CN-101410116-A | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-15 | — | — | CN | disclosed |
| JP-2008208047-A | METHOD FOR PRODUCING 1,3,4-TRIMETHYLPYRAZOLE-5-CARBOXYLATE, AND INTERMEDIATE FOR PRODUCING THE SAME | NISSAN CHEM IND LTD | 2008-09-11 | — | — | JP | disclosed |
| EP-0891975-A1 | PYRAZOLES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137413-A1 | NOVEL HALOGEN-SUBSTITUTED COMPOUNDS | CYP4F3, PYM1, PRDX4 | MAPT 4585/4885L3MBTL1 35/4885POLB 3825/4885 |
| US-20170114021-A1 | HALOGEN-SUBSTITUTED COMPOUNDS | PYM1, CYP4F3, ZYX | MAPT 4541/4885L3MBTL1 26/4885POLB 3602/4885 |
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | MAPT 4184/4885L3MBTL1 4/4885POLB 1708/4885 |
| US-20150099766-A1 | Novel halogen-substituted compounds | L3MBTL4, PRDX4, PRDX1 | MAPT 4164/4885L3MBTL1 5/4885POLB 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.