Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342558 | 0.86 | TAS1R3 (0.50) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10764969 | 0.85 | TSHR (0.66) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL758674 | 0.85 | TSHR (0.66) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10601731 | 0.85 | TSHR (0.66) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10335852 | 0.85 | TSHR (0.66) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27261725 | 0.85 | TSHR (0.56) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9036333 | 0.84 | TSHR (0.63) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10026167 | 0.82 | TSHR (0.61) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9050320 | 0.82 | TSHR (0.61) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10060163 | 0.82 | TSHR (0.61) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102199077-B | Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene | LU CHAO | 2013-01-23 | — | — | CN | claimed |
| CN-102199077-A | Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene | CHAO LU | 2011-09-28 | — | — | CN | claimed |
| CN-101891604-A | Method for synthesizing 2,4,5-trimethoxyethylphenylketone intermediate of alpha-asarin | GUANGXI TRADITIONAL CHINESE MEDICAL UNIVERSITY | 2010-11-24 | — | — | CN | claimed |
| CN-101195562-A | Novel method for synthesizing alpha-asarone | GUANGXI TRADITIONAL CHINESE ME (CN) | 2008-06-11 | — | — | CN | claimed |
| CN-102199077-B | Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene | LU CHAO | 2013-01-23 | — | — | CN | disclosed |
| CN-102199077-A | Method for producing (E)-2,4,5-trimethoxy-1-propenylbenzene | CHAO LU | 2011-09-28 | — | — | CN | disclosed |
| CN-101891604-A | Method for synthesizing 2,4,5-trimethoxyethylphenylketone intermediate of alpha-asarin | GUANGXI TRADITIONAL CHINESE MEDICAL UNIVERSITY | 2010-11-24 | — | — | CN | disclosed |
| JP-2008208134-A | PROCESS FOR PREPARATION OF PHARMACOLOGICALLY ACTIVE alpha-ASARONE DERIVED FROM TOXIC beta-ASARONE-RICH CALAMUS OIL | COUNCIL SCIENT IND RES | 2008-09-11 | — | — | JP | disclosed |
| CN-101195562-A | Novel method for synthesizing alpha-asarone | GUANGXI TRADITIONAL CHINESE ME (CN) | 2008-06-11 | — | — | CN | disclosed |
| EP-1487770-B1 | FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE | COUNCIL SCIENT IND RES (IN) | 2007-12-12 | — | — | EP | disclosed |
| US-6969778-B2 | DDQ mediated one step dimerization of β-asarone or β-asarone rich Acorus calamus oil in the formation of novel neolignan | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-11-29 | — | — | US | disclosed |
| EP-1487770-A1 | FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE | Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) | 2004-12-22 | — | — | EP | disclosed |
| US-20040049085-A1 | DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2004-03-11 | — | — | US | disclosed |
| WO-2003082786-A1 | A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ALPHA-ASARONE FROM TOXIC BETA-ASARONE RICH ACORUS CALAMUS OIL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | WO | disclosed |
| US-20030187306-A1 | DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2003-10-02 | — | — | US | disclosed |
| WO-2003080551-A1 | FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-02 | — | — | WO | disclosed |
| US-6590127-B1 | Formation of alpha-asarone, isoacoramone and 2,4,5-trimethoxycinnamaldehyde in one step process via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone assisted dehydrogenation/oxidation of 2,4,5-trimethoxyphenylpropane | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2003-07-08 | — | — | US | disclosed |
| US-20030113275-A1 | Process for the preparation of 1-Propyl-2, 4, 5- trimethoxybenzene from toxic beta-asarone of Acorus calamus or from crude calamus oil containing beta-asarone | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2003-06-19 | — | — | US | disclosed |
| US-6528041-B2 | Organoleptic | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-03-04 | — | — | US | disclosed |
| US-20020035299-A1 | Process for the preparation of 1-Propyl-2, 4, 5-trimethoxybenzene from toxic beta-asarone of acorus calamus or from crude calamus oil containing beta-asarone | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049085-A1 | DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan | DHPS, PTGES, PTGIS | TSHR 4748/4885CYP1A2 29/4885CYP3A4 254/4885 |
| US-20020035299-A1 | Process for the preparation of 1-Propyl-2, 4, 5-trimethoxybenzene from toxic beta-asarone of acorus calamus or from crude calamus oil containing beta-asarone | ADRA2B, CYP1B1, ADRB1 | TSHR 3018/4885CYP1A2 5/4885CYP3A4 47/4885 |
| US-20030187306-A1 | DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan | DHPS, PTGES, PTGIS | TSHR 4748/4885CYP1A2 29/4885CYP3A4 254/4885 |
| US-20030113275-A1 | Process for the preparation of 1-Propyl-2, 4, 5- trimethoxybenzene from toxic beta-asarone of Acorus calamus or from crude calamus oil containing beta-asarone | ADRA2B, CYP1B1, ADRB1 | TSHR 2977/4885CYP1A2 5/4885CYP3A4 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.