Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 14/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 6/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 5/20 | 0.42 |
| ▸ | PLA2G2E | Q9NZK7 | 5/20 | 0.42 |
| ▸ | PLA2G2F | Q9BZM2 | 2/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.42 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.41 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.41 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205580 | 0.89 | MEN1 (0.45) | PLA2G2AMTNR1AMTNR1BMAPTPKM | |
| SCHEMBL14531450 | 0.87 | UTS2R (0.41) | MTNR1AMTNR1BMAPTPKMALDH1A1 | |
| SCHEMBL4364785 | 0.86 | MAPK1 (0.49) | PLA2G2AMAPTPKMALDH1A1PLA2G1B | |
| SCHEMBL4764868 | 0.85 | PLA2G2A (0.48) | PLA2G2AMAPTPKMALDH1A1PLA2G1B | |
| SCHEMBL3186290 | 0.78 | TSHR (0.50) | PLA2G2AMAPTPKMALDH1A1KDM4E | |
| SCHEMBL3196227 | 0.76 | SQOR (0.45) | PLA2G2AMAPTALDH1A1PLA2G1BPLA2G10 | |
| SCHEMBL3198895 | 0.74 | BRD4 (0.46) | PLA2G2AMAPTPKMALDH1A1KDM4E | |
| SCHEMBL8502661 | 0.74 | MTNR1A (0.53) | PLA2G2AMTNR1AMTNR1BMAPTPKM | |
| SCHEMBL22533505 | 0.73 | DCTPP1 (0.40) | MTNR1AMTNR1BMAPT | |
| SCHEMBL5765082 | 0.73 | PKM (0.43) | PLA2G2AMTNR1AMTNR1BMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960356-A2 | MULTIVALENT INDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | Ilypsa, Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1948656-A2 | AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | Ilypsa, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007056281-A2 | MULTIVALENT INDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056184-A2 | AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |