Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762978 | 0.82 | BCAT2 (0.44) | CDC7NUDT1CCNE2CCNE1CDK2 | |
| SCHEMBL4770932 | 0.81 | NUDT1 (0.41) | CDC7NUDT1CCNE2CCNE1CDK2 | |
| SCHEMBL7428184 | 0.80 | TDO2 (0.40) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL4768889 | 0.78 | NUDT1 (0.58) | NUDT1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL27740539 | 0.73 | KDM4E (0.47) | CDC7BTKKEAP1NFE2L2KDM4E | |
| SCHEMBL1694890 | 0.70 | KDM4E (0.45) | NUDT1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL2417969 | 0.68 | ALDH1A1 (0.49) | BTKKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL3559657 | 0.67 | ALDH1A1 (0.54) | BTKKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL27484628 | 0.67 | ALDH1A1 (0.58) | CDC7BTKKEAP1NFE2L2KDM4E | |
| SCHEMBL17237437 | 0.65 | SIRT3 (0.51) | CDC7BTKKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | claimed |