Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.39 |
| ▸ | CPN1 | P15169 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CIT | O14578 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099315 | 0.81 | ARG1 (0.43) | CPB2CPN1KMT2AKDM4EMAPT | |
| SCHEMBL4769110 | 0.80 | CPB2 (0.42) | CPB2CPN1 | |
| SCHEMBL4769116 | 0.80 | CPB2 (0.42) | CPB2CPN1 | |
| SCHEMBL6206698 | 0.74 | KDM4E (0.38) | CPB2CPN1KMT2AKDM4EMAPT | |
| SCHEMBL5096660 | 0.74 | CTSS (0.56) | CPB2 | |
| SCHEMBL27206103 | 0.73 | KMT2A (0.44) | CPB2KMT2AEPHX1LMNASMN1; SMN2 | |
| SCHEMBL27192634 | 0.73 | KMT2A (0.44) | CPB2KMT2AEPHX1LMNASMN1; SMN2 | |
| SCHEMBL6217307 | 0.73 | METAP2 (0.42) | KMT2AMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL27206119 | 0.71 | KMT2A (0.43) | CPB2KMT2AEPHX1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27192716 | 0.71 | KMT2A (0.43) | CPB2KMT2AEPHX1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052365-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052365-A1 | Protease inhibitors | CTSS, CTSE, CMA1 | CPB2 57/4885CPN1 25/4885KMT2A 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.