Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 2/20 | 0.56 |
| ▸ | PRKCA | P17252 | 2/20 | 0.56 |
| ▸ | PRKCH | P24723 | 2/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771287 | 0.95 | ROCK2 (0.60) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL4770812 | 0.82 | HRH4 (0.56) | KMT2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4772233 | 0.81 | MERTK (0.55) | KDM4EALDH1A1POLBGAAACP1 | |
| SCHEMBL4766376 | 0.81 | KMT2A (0.46) | KMT2AKDM4EALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL4769484 | 0.81 | MERTK (0.54) | KDM4EALDH1A1POLBGAAACP1 | |
| SCHEMBL4768596 | 0.81 | SMN1; SMN2 (0.46) | KMT2AMEN1PKMSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL4766731 | 0.80 | KMT2A (0.45) | KMT2AALDH1A1POLBGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6288704 | 0.80 | KMT2A (0.45) | KMT2AALDH1A1POLBGAAMEN1 | |
| SCHEMBL4763566 | 0.80 | HRH3 (0.48) | ROCK2ROCK1PKN2KMT2AKDM4E | |
| SCHEMBL4772049 | 0.80 | LMNA (0.47) | KMT2AKDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
| US-6790844-B2 | MUSCLE RELAXANTS; ANTISEROTONINE AGENT | EISAI CO., LTD (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | PRKCB 4169/4885PRKCA 3763/4885PRKCH 3746/4885 |
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | PRKCB 3628/4885PRKCA 3220/4885PRKCH 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.