SCHEMBL4771287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4770751	0.95	PRKCB (0.56)	ROCK2ROCK1PKN2KDM4EALDH1A1
	SCHEMBL4770812	0.86	HRH4 (0.56)	KDM4EKMT2ACYP1A2CYP3A4CYP2D6
	SCHEMBL4772233	0.85	MERTK (0.55)	KDM4EALDH1A1POLBGAAACP1
	Hydrochloric Acid SCHEMBL4769484	0.84	MERTK (0.54)	KDM4EALDH1A1POLBGAAACP1
	SCHEMBL4772049	0.83	LMNA (0.47)	KDM4EALDH1A1POLBGAAKMT2A
	SCHEMBL4763566	0.83	HRH3 (0.48)	ROCK2ROCK1PKN2KDM4EALDH1A1
	SCHEMBL4774137	0.83	TLR9 (0.52)	ROCK2ROCK1PKN2KDM4EALDH1A1
	Hydrochloric Acid SCHEMBL4774712	0.82	TLR9 (0.51)	ROCK2ROCK1PKN2KDM4EALDH1A1
	Hydrochloric Acid SCHEMBL4770729	0.82	HRH3 (0.47)	ROCK2ROCK1PKN2ALDH1A1GAA
	SCHEMBL4765804	0.82	TLR9 (0.48)	KDM4EALDH1A1GAAKMT2APRKD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.