Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4765747 | 0.95 | MET (0.46) | METKDRSMN1; SMN2MAPTMEN1 | |
| SCHEMBL4773051 | 0.81 | MAPT (0.56) | METSMN1; SMN2MAPTALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4774586 | 0.77 | MAPT (0.51) | METSMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL4774462 | 0.77 | RAB9A (0.59) | SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4765386 | 0.77 | TP53 (0.55) | METSMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL4765424 | 0.77 | HRH3 (0.47) | SMN1; SMN2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL5459684 | 0.76 | HRH3 (0.53) | SMN1; SMN2MEN1KMT2ATP53POLB | |
| SCHEMBL4770555 | 0.76 | NPC1 (0.51) | SMN1; SMN2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL4777120 | 0.76 | NPY5R (0.54) | METKDRSMN1; SMN2MAPTTP53 | |
| SCHEMBL4768161 | 0.76 | POLB (0.56) | SMN1; SMN2MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |