Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120132 | 0.78 | ADRB2 (0.33) | — | |
| SCHEMBL6119962 | 0.77 | CYP2C19 (0.37) | CA2 | |
| SCHEMBL22284107 | 0.75 | LMNA (0.40) | FAAHTDP1CNR1CNR2POLB | |
| SCHEMBL12898519 | 0.74 | ADRB2 (0.34) | FAAHTDP1CNR1CNR2POLB | |
| SCHEMBL6120126 | 0.74 | CA2 (0.33) | CA2 | |
| SCHEMBL1265501 | 0.74 | ADRB2 (0.34) | FAAHTDP1CNR1CNR2POLB | |
| SCHEMBL22284117 | 0.73 | CYP2C19 (0.38) | FAAHTDP1POLB | |
| SCHEMBL6119903 | 0.73 | APLNR (0.36) | — | |
| SCHEMBL6119527 | 0.73 | CA2 (0.32) | CA2 | |
| SCHEMBL2500618 | 0.71 | ADRB2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874772-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108103-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2006-10-12 | — | — | WO | disclosed |