Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381502 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL13717627 | 0.70 | TDP1 (0.32) | — | |
| SCHEMBL25137333 | 0.69 | FAAH (0.43) | ALDH1A1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL25137362 | 0.65 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL23635286 | 0.63 | — | — | |
| SCHEMBL6100549 | 0.63 | TDP1 (0.35) | ALDH1A1HPGDRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11619600 | 0.62 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL11609722 | 0.61 | KMT2A (0.43) | ALDH1A1MAPTHPGDRAB9AKMT2A | |
| SCHEMBL11222290 | 0.61 | — | — | |
| SCHEMBL20214069 | 0.61 | RAB9A (0.33) | ALDH1A1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240074301-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| US-20230120996-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-04-20 | — | — | US | disclosed |
| EP-1549316-A4 | INHIBITORS OF TFGbeta | SCIOS INC (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-1549316-A1 | INHIBITORS OF TFG&bgr; | SCIOS INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040132730-A1 | Inhibitors of TGFbeta | SCIOS, INC. | 2004-07-08 | — | — | US | disclosed |
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004024159-A1 | INHIBITORS OF TFGβ | SCIOS INC. (US) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240074301-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ICOSLG, OCIAD2, OSBP | ALDH1A1 658/4885MAPT 1707/4885HPGD 1374/4885 |
| US-20040132730-A1 | Inhibitors of TGFbeta | TGFBR1, TGFBR2, TGFB1 | ALDH1A1 2530/4885MAPT 2390/4885HPGD 1323/4885 |
| US-20230120996-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ICOSLG, OCIAD2, OSBP | ALDH1A1 658/4885MAPT 1707/4885HPGD 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.