Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643508 | 0.91 | IDO1 (0.40) | MAOAMAOBSMN1; SMN2OPRM1ALDH1A1 | |
| SCHEMBL10728607 | 0.84 | TSHR (0.35) | MAOAMAOBOPRM1ALDH1A1IDO1 | |
| SCHEMBL477537 | 0.76 | KDM1A (0.35) | MAOAMAOBOPRM1ALDH1A1 | |
| SCHEMBL338864 | 0.74 | SIGMAR1 (0.37) | MAOAOPRM1TAAR1 | |
| SCHEMBL28127207 | 0.74 | HTR1A (0.34) | HTR1AADRA1DADRA1B | |
| SCHEMBL16243044 | 0.73 | OPRM1 (0.37) | MAOAMAOBOPRM1 | |
| SCHEMBL60702 | 0.72 | MAOA (0.41) | MAOAMAOBHTR1AOPRM1ALDH1A1 | |
| SCHEMBL28051698 | 0.72 | HTR1A (0.33) | HTR1AADRA1DADRA1B | |
| SCHEMBL1837501 | 0.72 | MAPT (0.31) | — | |
| SCHEMBL2170086 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017528-A | HYDROLYTIC POLYCONDENSATION OF TETRAALKOXYSILANES OR POLYALKOXYSILOXANES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-12 | — | — | US | disclosed |