Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781031 | 0.82 | GAA (0.40) | MAPTGAATSHRLMNAHTR1A | |
| SCHEMBL4774183 | 0.81 | NPC1 (0.37) | SIGMAR1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4776044 | 0.81 | RORC (0.41) | CNR2 | |
| SCHEMBL4780839 | 0.78 | SLC6A2 (0.44) | SIGMAR1LMNA | |
| SCHEMBL4778958 | 0.78 | ADRA1D (0.48) | SIGMAR1MAPTOPRM1MAPK1 | |
| SCHEMBL4779434 | 0.78 | ADRA1D (0.48) | SIGMAR1MAPTOPRM1MAPK1 | |
| SCHEMBL4775240 | 0.76 | MEN1 (0.41) | SIGMAR1MAPTTSHRMEN1KMT2A | |
| SCHEMBL23199732 | 0.75 | SIGMAR1 (0.59) | SIGMAR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18484463 | 0.75 | KMT2A (0.41) | SIGMAR1TSHRMEN1KMT2A | |
| SCHEMBL14820140 | 0.75 | KMT2A (0.41) | SIGMAR1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |