Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20483701 | 0.90 | — | — | |
| Fluoride Ion SCHEMBL131861 | 0.90 | ALDH1A1 (0.33) | — | |
| Potassium Ion SCHEMBL27574503 | 0.90 | ALDH1A1 (0.33) | — | |
| Fluoride Ion SCHEMBL963997 | 0.90 | — | — | |
| Iodide SCHEMBL12479772 | 0.90 | — | — | |
| Potassium Ion SCHEMBL6573907 | 0.90 | — | — | |
| Fluoride Ion SCHEMBL2867038 | 0.90 | — | — | |
| Fluoride Ion SCHEMBL728564 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL124190 | 0.89 | — | — | |
| SCHEMBL30 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520422-A | Novel pyridone carboxylic acid derivatives or its salt | WAKUNAGA PHARMA CO LTD | 2019-11-29 | — | — | CN | disclosed |
| EP-1635413-B1 | PROTON CONDUCTIVE FILM, METHOD FOR PRODUCING SAME, AND FUEL CELL USING SAME | SEKISUI CHEMICAL CO LTD (JP) | 2012-02-01 | — | — | EP | disclosed |
| CN-1806357-A | Proton conductive film, method for producing the same, and fuel cell using same | SEKISUI CHEMICAL CO LTD (JP) | 2006-07-19 | — | — | CN | disclosed |