SCHEMBL9908176

SCHEMBL9908176

COc1cc(C(C)=O)c([N+](=O)[O-])cc1O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 3/20 0.48
POLB P06746 2/20 0.48
MAPT P10636 1/20 0.47
NPC1 O15118 1/20 0.46
CYP3A4 P08684 1/20 0.46
PKM P14618 2/20 0.44
TPMT P51580 1/20 0.44
ABCB1 P08183 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30716507 0.88 L3MBTL1 (0.59) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL4108486 0.88 L3MBTL1 (0.59) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL16945800 0.87 PKM (0.55) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL5502239 0.86 POLB (0.47) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL29734700 0.86 POLB (0.50) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL5256629 0.86 POLB (0.50) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL19514652 0.84 L3MBTL1 (0.49) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL12779095 0.84 L3MBTL1 (0.49) HTTL3MBTL1LMNAPOLBMAPT
SCHEMBL4776517 0.83 SNCA (0.50) MAPTCYP3A4KDM4E
SCHEMBL29538041 0.83 SNCA (0.50) MAPTCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377651-A Cationic lipid with side chain containing functional groups and application thereof 厦门赛诺邦格生物科技股份有限公司 2024-01-09 CN claimed
WO-2023126006-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2023-07-06 WO claimed
CN-115197080-A Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2022-10-18 CN claimed
CN-115197079-A Polyethylene glycol lipid and liposome modified by same, pharmaceutical composition containing liposome, preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2022-10-18 CN claimed
CN-115010915-A Nitrogen branched nine-arm polyethylene glycol derivative, preparation method and biological related substance modified by nitrogen branched nine-arm polyethylene glycol derivative 厦门赛诺邦格生物科技股份有限公司 2022-09-06 CN claimed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-113429559-A Six-arm polyethylene glycol derivative with end hetero-functionalized and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2021-09-24 CN claimed
CN-113402405-A Cationic lipid, liposome containing cationic lipid, nucleic acid pharmaceutical composition containing liposome, preparation and application thereof 厦门赛诺邦格生物科技股份有限公司 2021-09-17 CN claimed
CN-108530636-B Single functionalized branched polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2021-05-28 CN claimed
CN-112694608-A Six-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2021-04-23 CN claimed
CN-108530617-B Branched polyethylene glycol heterobifunctional derivative, preparation method thereof and two-component bio-related substance conjugate thereof 厦门赛诺邦格生物科技股份有限公司 2020-11-27 CN claimed
CN-108976758-B Photosensitive polyethylene glycol-based antibacterial hydrogel dressing and preparation method thereof 浙江大学 2020-09-01 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US claimed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US claimed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP claimed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US claimed
CN-112694608-B Six-arm polyethylene glycol derivative, preparation method and modified biological related substance 厦门赛诺邦格生物科技股份有限公司 2024-07-02 CN disclosed
US-7198893-B1 DNA diagnostics based on mass spectrometry SEQUENOM, INC. (US) 2007-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A HTT 4558/4885L3MBTL1 939/4885LMNA 4044/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 HTT 4565/4885L3MBTL1 744/4885LMNA 3842/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 HTT 3622/4885L3MBTL1 512/4885LMNA 826/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 HTT 3622/4885L3MBTL1 512/4885LMNA 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.