Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428124 | 0.92 | CTSD (0.46) | CNR2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL341330 | 0.90 | NPC1 (0.53) | CNR2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL31074983 | 0.90 | NPC1 (0.53) | CNR2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4778742 | 0.83 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL699716 | 0.82 | ALDH1A1 (0.45) | CNR2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL4746226 | 0.80 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL8658218 | 0.80 | MAPK1 (0.58) | CNR2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL27903906 | 0.80 | HTT (0.56) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL196440 | 0.80 | MGAM (0.55) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL29248144 | 0.79 | CA12 (0.58) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940372-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | Revotar Biopharmaceuticals AG (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007039113-A1 | NOVEL AROMATIC COMPOUNDS AND THEIR USE IN MEDICAL APPLICATIONS | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |