Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776201 | 1.00 | ROCK2 (0.42) | ROCK2ROCK1FABP4DAGLBDAGLA | |
| SCHEMBL4777579 | 0.92 | HSD17B2 (0.43) | FABP4HSD17B2 | |
| SCHEMBL8221589 | 0.84 | GPR119 (0.43) | — | |
| SCHEMBL4779673 | 0.84 | PIM2 (0.42) | FABP4 | |
| SCHEMBL4726621 | 0.84 | DAGLB (0.42) | FABP4DAGLBDAGLACTSLCTSK | |
| SCHEMBL4726619 | 0.84 | DAGLB (0.42) | FABP4DAGLBDAGLACTSLCTSK | |
| SCHEMBL4776097 | 0.82 | ROCK2 (0.42) | ROCK2ROCK1HSD17B2 | |
| SCHEMBL4776087 | 0.82 | ROCK2 (0.42) | ROCK2ROCK1HSD17B2 | |
| SCHEMBL4725342 | 0.80 | HPGD (0.41) | DAGLAHSD17B2 | |
| SCHEMBL3076594 | 0.80 | LMNA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |