Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779433 | 0.90 | PTGDR2 (0.50) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4779470 | 0.89 | KDM4E (0.42) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4778231 | 0.89 | KDM4E (0.46) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4774108 | 0.88 | KDM4E (0.44) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4776203 | 0.88 | KDM4E (0.46) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4707696 | 0.86 | PTGDR2 (0.47) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4780894 | 0.86 | LMNA (0.47) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4780709 | 0.86 | KMT2A (0.38) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4780527 | 0.85 | SMN1; SMN2 (0.42) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4773925 | 0.85 | POLB (0.42) | KDM4ETSHRPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008000818-A1 | FLUORINATED INDOLEAMIDES USEFUL AS LIGANDS OF THE ORL-1 RECEPTOR | BRANE DISCOVERY S.R.L. (IT) | 2008-01-03 | — | — | WO | disclosed |