Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780556 | 0.94 | KDM4E (0.46) | CNR2CNR1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4708685 | 0.90 | HTR6 (0.43) | LMNAGLAL3MBTL1KDM4EPOLB | |
| SCHEMBL4708187 | 0.88 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19KDM4EHRH1 | |
| SCHEMBL4780894 | 0.85 | LMNA (0.47) | LMNAGLAL3MBTL1KDM4EHRH1 | |
| SCHEMBL4776252 | 0.85 | PTGDR2 (0.44) | CNR2CNR1CYP3A4CYP2C19KDM4E | |
| SCHEMBL4780527 | 0.84 | SMN1; SMN2 (0.42) | LMNAGLAL3MBTL1KDM4EPOLB | |
| SCHEMBL4773925 | 0.84 | POLB (0.42) | LMNAGLAL3MBTL1KDM4EPOLB | |
| SCHEMBL4774098 | 0.84 | PTGDR2 (0.41) | LMNAGLAL3MBTL1PTGDR2 | |
| SCHEMBL4706301 | 0.82 | KDM4E (0.44) | CYP3A4CYP2C9CYP2C19KDM4EHRH1 | |
| SCHEMBL4708952 | 0.82 | CNR2 (0.41) | CNR2CNR1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008000818-A1 | FLUORINATED INDOLEAMIDES USEFUL AS LIGANDS OF THE ORL-1 RECEPTOR | BRANE DISCOVERY S.R.L. (IT) | 2008-01-03 | — | — | WO | claimed |
| WO-2008000818-A1 | FLUORINATED INDOLEAMIDES USEFUL AS LIGANDS OF THE ORL-1 RECEPTOR | BRANE DISCOVERY S.R.L. (IT) | 2008-01-03 | — | — | WO | disclosed |