Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709394 | 0.96 | PTGS2 (0.43) | PTGDR2PTGS2HTR6MAPTLMNA | |
| SCHEMBL4708685 | 0.93 | HTR6 (0.43) | PTGDR2HTR6MAPTLMNAGLA | |
| SCHEMBL4709041 | 0.90 | PTGS2 (0.40) | PTGS2MAPTLMNAEGFRTYMS | |
| SCHEMBL4773925 | 0.88 | POLB (0.42) | PTGDR2HTR6MAPTLMNAGLA | |
| SCHEMBL4708187 | 0.86 | CYP3A4 (0.44) | PTGS2MAPTEGFRTYMSLTA4H | |
| Trifluoroacetic Acid SCHEMBL4518616 | 0.85 | MAPT (0.42) | PTGS2MAPTLMNAGLAL3MBTL1 | |
| SCHEMBL4779231 | 0.84 | CNR2 (0.46) | PTGDR2LMNAGLAL3MBTL1 | |
| SCHEMBL4706301 | 0.81 | KDM4E (0.44) | PTGS2MAPTEGFRTYMSLTA4H | |
| SCHEMBL4780894 | 0.80 | LMNA (0.47) | PTGDR2MAPTLMNAGLAL3MBTL1 | |
| SCHEMBL4776252 | 0.80 | PTGDR2 (0.44) | PTGDR2HTR6MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008000818-A1 | FLUORINATED INDOLEAMIDES USEFUL AS LIGANDS OF THE ORL-1 RECEPTOR | BRANE DISCOVERY S.R.L. (IT) | 2008-01-03 | — | — | WO | claimed |