Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL1887306 | 0.95 | TSHR (0.62) | DAOTSHRNAPRTSRD5A2CES2 | |
| SCHEMBL1926270 | 0.93 | HDAC1 (0.64) | DAOTSHRNAPRTSRD5A2CES2 | |
| SCHEMBL8894364 | 0.93 | HDAC1 (0.64) | DAOTSHRNAPRTSRD5A2CES2 | |
| Hydrochloric Acid SCHEMBL7704996 | 0.91 | HDAC1 (0.62) | DAOTSHRNAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL22638831 | 0.89 | TDP1 (0.70) | DAOTSHRNAPRTSRD5A2CES2 | |
| SCHEMBL30395109 | 0.87 | FOLH1 (0.66) | DAONR4A2FOLH1 | |
| Phenethylamine SCHEMBL28384786 | 0.87 | HTR2A (0.67) | DAOTSHRNAPRTSRD5A2CES2 | |
| SCHEMBL1817886 | 0.87 | FOLH1 (0.66) | DAONR4A2FOLH1 | |
| Phenyl Propionic Acid SCHEMBL5786016 | 0.87 | KEAP1 (0.79) | DAOTSHRNAPRTFFAR1NPC1 | |
| Benzoic Acid SCHEMBL28227657 | 0.87 | DAO (0.58) | DAOTSHRNAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070856-B2 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A-Son Enterprise, Inc. (JP) | 2006-07-04 | — | — | US | claimed |
| US-20030170457-A1 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A SON ENTERPRISE INC (JP) | 2003-09-11 | — | — | US | claimed |
| EP-1326128-A2 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A-Son Enterprize Inc. (JP) | 2003-07-09 | — | — | EP | claimed |
| US-9858907-B2 | Method of gripping a striking apparatus | Racine Daniel Paul (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160249697-A1 | Method Of Gripping A Striking Apparatus | Racine Daniel Paul (US) | 2016-09-01 | — | — | US | disclosed |
| EP-1326128-B1 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | CHEMITECH INC (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7378374-B2 | Thermally sensitive recording medium | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| US-20060292361-A1 | Front face erasable microcapsule magnetophoretic writing magnet | TOCOM CORPORATION (JP) | 2006-12-28 | — | — | US | disclosed |
| US-20060147754-A1 | Front face erasable microcapsule magnetophoretic erasing magnet | TOCOM CORPORATION (JP) | 2006-07-06 | — | — | US | disclosed |
| US-7070856-B2 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A-Son Enterprise, Inc. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20060093858-A1 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A SON ENTERPRISE, INC. | 2006-05-04 | — | — | US | disclosed |
| US-20030170457-A1 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A SON ENTERPRISE INC (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1326128-A2 | Front face erasable microcapsule magnetophoretic display sheet, erasing magnet and writing magnet | A-Son Enterprize Inc. (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1255438-A1 | SYSTEMS FOR CONTROLLING PLANT AND FLOWER MOISTURE TRANSPIRATION RATES | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| US-20020006873-A1 | Systems for controlling plant and flower moisture transpiration rates | PROCTER & GAMBLE COMPANY, THE | 2002-01-17 | — | — | US | disclosed |
| WO-2001050856-A1 | SYSTEMS FOR CONTROLLING PLANT AND FLOWER MOISTURE TRANSPIRATION RATES | THE PROCTER & GAMBLE COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-0583377-B1 | ONE PACKAGE POLYURETHANE/THERMOPLAST PLASTISOL COMPOSITION | HENKEL TEROSON GMBH (DE) | 1998-10-07 | — | — | EP | disclosed |
| EP-0583377-A1 | ONE PACKAGE POLYURETHANE/THERMOPLAST PLASTISOL COMPOSITION | Henkel Teroson GmbH (DE) | 1994-02-23 | — | — | EP | disclosed |
| US-5284918-A | Blocked isocyanate prepolymer and a cycloaliphatic curing agent | W. R. GRACE & CO.-CONN. (US) | 1994-02-08 | — | — | US | disclosed |
| WO-1992019662-A1 | ONE PACKAGE POLYURETHANE/THERMOPLAST PLASTISOL COMPOSITION | W.R. GRACE & CO.-CONN. (US) | 1992-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006873-A1 | Systems for controlling plant and flower moisture transpiration rates | TREH, CUTA, FIS1 | DAO 3262/4885TSHR 2181/4885NAPRT 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.