Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781178 | 0.87 | UBE2M (0.39) | POLBMAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL4779787 | 0.85 | FFAR4 (0.38) | POLBMEN1KMT2ACYP2C19LMNA | |
| SCHEMBL4321609 | 0.76 | GRM5 (0.42) | DRD2MEN1KMT2AALDH1A1 | |
| SCHEMBL4780326 | 0.76 | CHRM4 (0.40) | DRD2HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL4778369 | 0.75 | NOTUM (0.40) | DRD2DRD4POLBMEN1KMT2A | |
| SCHEMBL4780977 | 0.75 | ALOX15 (0.38) | DRD2 | |
| SCHEMBL4774338 | 0.75 | DRD2 (0.32) | DRD2HTTTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4778958 | 0.75 | ADRA1D (0.48) | DRD2DRD4MAPTCYP2C19ALDH1A1 | |
| SCHEMBL4779434 | 0.75 | ADRA1D (0.48) | DRD2DRD4MAPTCYP2C19ALDH1A1 | |
| SCHEMBL4779536 | 0.75 | DRD2 (0.32) | DRD2HTTTDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |