Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP19 | O94966 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873480 | 1.00 | NAMPT (0.41) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL27889764 | 1.00 | NAMPT (0.41) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL4772640 | 0.94 | NAMPT (0.37) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL18855618 | 0.87 | ALDH1A1 (0.43) | NAMPTRIPK1USP19 | |
| SCHEMBL2830943 | 0.85 | NAMPT (0.40) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL8577326 | 0.84 | CA2 (0.47) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL8575754 | 0.84 | CA2 (0.47) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL10075387 | 0.83 | NAMPT (0.39) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL22468655 | 0.83 | NAMPT (0.39) | NAMPTPOLBL3MBTL1SCD5VNN1 | |
| SCHEMBL18686787 | 0.83 | SCD5 (0.40) | NAMPTPOLBL3MBTL1SCD5VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364246-A | Piperidine derivatives useful as GPR119 agonists | TOYOTA MOTOR CO LTD | 2015-02-18 | — | — | CN | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | disclosed |
| CN-104364246-A | Piperidine derivatives useful as GPR119 agonists | TOYOTA MOTOR CO LTD | 2015-02-18 | — | — | CN | disclosed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |