Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782243 | 0.78 | — | — | |
| SCHEMBL3844734 | 0.75 | PGR (0.36) | — | |
| SCHEMBL6741105 | 0.72 | NOTUM (0.36) | — | |
| SCHEMBL18518447 | 0.72 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL5822962 | 0.72 | NOTUM (0.41) | ALDH1A1HTTKMT2A | |
| SCHEMBL4783515 | 0.70 | CHEK1 (0.32) | — | |
| SCHEMBL4244577 | 0.70 | DAO (0.44) | GAAAPOBEC3GHPGDALDH1A1ALOX12 | |
| SCHEMBL8784377 | 0.69 | CYP2A6 (0.45) | — | |
| SCHEMBL4783082 | 0.69 | HMBS (0.34) | — | |
| SCHEMBL10457975 | 0.69 | NOTUM (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |